KMID : 0043319990220010075
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Archives of Pharmacal Research 1999 Volume.22 No. 1 p.75 ~ p.77
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Inhibitory Constituents against HIV-1 Protease from Agastache rugosa
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Min Byung-Sun
Masao-Hattori Lee Hyeong-Kyu Kim Young-Ho
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Abstract
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Two diterpenoid compounds, agastanol (1) and agastaquinone (2), were isolated from the roots of Agastache rugosa (Labiatae). Compound 1 and 2 showed significant inhibitory effects against human immunodeficiency virus type 1 (HIV-1) protease activity with values of 360 and , respectively.
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KEYWORD
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Agastache rugosa, Labiatae, Agastanol, Agastaquinone, Anti-HIV-1 protease activity
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